There is a deluge of data across many scientific disciplines. Future scientific breakthroughs will rely on algorithms to explore these massive data. Our group develops machine learning algorithms to automatically generate scientific discoveries from large-scale datasets comprising thousands of subjects with brain magnetic resonance imaging (MRI), behavioral, genetic and other physiological measures. 

Information processing in the human brain arises from 100 billion neurons connected by 100 trillion synapses into a complex network. MRI allows us to non-invasively study brain networks of living individuals. By exploring large multi-modal datasets, we seek to discover fundamental principles of brain network organization, how brain networks are organized to support cognition and how brain networks are disrupted in mental disorders.
News  
  • 04/2018: Congrats to Siyi for admittance into Stanford EE PhD program
  • 03/2018: Thomas presented Alex's and Ruby's work on brain parcellation at Whistler's workshop
  • 02/2018: Thomas presented Xiuming's and Nanbo's work on Alzheimer's Disease subtypes at EUROPOND 2018
  • 12/2017: Our paper on interpreting dynamic functional connectivity is out in NeuroImage [pdf]
  • ​12/2017: Michael Breakspear (QIMR Berghofer) visited our group​
  • ​11/2017: Our paper on the diverse club is out in Nature Communications [pdf]
  • 10/2017: CM Ting (Universiti Teknologi Malaysia) visited our group
  • 08/2017: JB Poline (McGill) and Russ Poldrack (Stanford) visited our group
  • 08/2017: Welcome Valeria, Jianzhong, Xiaolu, Qing Yang, Jeremy and Alisia to our group
  • 08/2017: Thomas started his NRF fellowship on mental disorder subtypes
  • 07/2017: Our new local-global cortical parcellation is out in Cerebral Cortex [pdf]
  • 07/2017: Welcome Nicole Kuek to our group
  • 04/2017: Thomas received the NUS Young Researcher Award
  • 03/2017: Our commentary on multiscale neuroscience is out in Neuron [pdf]
  • 03/2017: Welcome Siyi Tang to our group
  • 03/2017: Lucina Uddin (University of Miami) visited our group
  • 02/2017: Congrats to Gia for admittance into Cornell ECE PhD program
  • 02/2017: Our commentary on best practices in data analysis and sharing in neuroimaging using MRI is out in Nature Neuroscience [pdf]
  • 02/2017: Tom Nichols (Warwick) visited our group
  • 11/2016: Congrats to Xilin for Rhodes Scholarship to Oxford
  • 11/2016: Itamar Kahn (Technion) visited our group
  • 10/2016: Our paper on latent atrophy factors in Alzheimer's Disease is out in PNAS [free download] [NUS press release] [MGH press release] [science daily] [upi]
  • 08/2016: Our paper on the collapsed variation Bayes inference of the author-topic model is out in PRNI [pdf]
  • 08/2016: Welcome Wenyan Hu, Tong He, Chu-Ming Chang and Csaba Orban to our team
  • 07/2016: Daniel Rueckert (Imperial College) visited our group
  • 07/2016: Commentary with Simon Eickhoff (Heinrich-Heine) is out in Nature [commentary pdf] [scientific american, huffington post, vice, popular science, geekwire]
  • ​07/2016: Welcome Minh Binh Nguyen and Ke Wang to our team
  • 06/2016: Congrats to Ruby for OHBM merit abstract award
  • ​06/2016: Welcome Rajan Kashyap to our team
  • 05/2016: Congrats to Ruby and Xiuming for ISMRM educational awards
  • 05/2016: Daniel Alexander (UCL), Jonathan Polimeni (HMS), Steve Smith (Oxford) and Anastasia Yendiki (HMS) visited our group
  • 05/2016: Welcome Peng Wang and Muhammad Anwar to our team
  • 04/2016: Simon Eickhoff (Heinrich-Heine) visited our group
  • 03/2016: Suzanne Haber (University of Rochester) visited our group
  • 02/2016: Welcome Dragana Pavlovic to our team
  • 01/2016: Thomas is now editor of NeuroImage
  • 01/2016: Rodolphe Sepulchre (Cambridge) visited our group
  • 01/2016: Our paper on the genetic architecture of cortical networks is out in PNAS [pdf] [medicalxpress news]
  • 11/2015: Our paper on the modular and integrative structure of the human brain is out in PNAS [pdf] [Berkeley press release]
  • 11/2015: Welcome Raphael Liegeois to our team
  • 10/2015: Commentary with Avram Holmes (Yale) out in Nature Neuroscience [commentary pdf] [Steve's awesome paper]
  • 08/2015: Welcome Jingwei Li, Nanbo Sun, Rensheng Liu to our team
  • 05/2015: Daniel Margulies (Max Planck) visited our group
  • 05/2015: Welcome Jianxiao Wu, Binbin Tang and Yuanhao Gong to our team
  • 03/2015: Tom Nichols (Warwick) visited our group
  • 03/2015: Congrats to Alex for being awarded the German DAAD Postdoctoral Fellowship
  • 03/2015: Our paper on predicting sleep deprivation vulnerability with functional connectivity is out in Neuroimage [pdf]
  • 02/2015: New MOE Tier 2 grant for estimating brain networks from resting-state fMRI and meta-analytic fMRI
  • 02/2015: Congrats to Xiuming for admittance into MIT EECS PhD program
  • 01/2015: Welcome Buu Vinh Tang to our team
  • 10/2014: Our meta-analysis of 10,449 imaging experiments is out in Cerebral Cortex [pdf] [interactive ontology]
  • 09/2014: New NUS Strategic Research Grant for studying memory networks in rodents and primates
  • 08/2014: Polina Golland (MIT) visited our group
  • 08/2014: Welcome Ruby Ru, Xiuming Zhang and Ngo Hoang Gia to our team
  • 07/2014: Welcome Alexander Schaefer to our team